Offensive: Although this unit may be a Super Rare unit, be wary that it is one of the weakest Super Rare units out there. It can only barely take out a Centaur without getting itself killed, too. However, if your squad doesn't have a good anti-infantry weapon, use this, as it can very easily kill infantry soldiers. On some campaign missions, where the enemy swarms Rocket Squads at you, this can actually help you.
Defensive: The Death's Head has extremely low defense for a Super Rare unit. Since it has a range of 25, sniper units can take them out, as well as any other non-infantry units that are uncommon or better.